Sequoya Biotechnologies expands its contract manufacturing portfolio with a new collagen product line, offering 25 ml ready-to-drink collagen shots and liquid collagen concentrates for brands seeking differentiated beauty-from-within and wellness products.
Collagen Is Moving From Trend to Product Category
Collagen has become one of the most recognisable ingredients in the beauty, wellness and functional nutrition markets. For supplement brands, the opportunity is no longer limited to adding collagen powder to a traditional product. Liquid formats, convenient serving concepts and differentiated formulations are creating new ways to build collagen products around modern consumer routines.
Sequoya Biotechnologies is expanding its contract manufacturing portfolio with a dedicated white label and private label collagen product line. The range is built around two formats: 25 ml ready-to-drink collagen shots and larger-format liquid collagen concentrates.
The Collagen Market: Why Brands Are Paying Attention
Market estimates vary depending on how collagen is defined — collagen as a raw-material category, collagen supplements, collagen peptides or the wider collagen market. However, the direction is consistent: collagen is a substantial and growing category.
Grand View Research estimates the global collagen market at USD 11.4 billion in 2025, with a projected CAGR of 10.9% from 2026 to 2033. Europe represented the largest regional share at 35.3% in 2025.
Grand View Research — Collagen Market, 2026–2033
Looking specifically at dietary supplements, Grand View Research estimates the global collagen dietary supplements market at approximately USD 5.98 billion in 2025 and projects it to reach USD 16.78 billion by 2033, representing a 13.8% CAGR.
Grand View Research — Collagen Dietary Supplements Market Statistics
European market estimates also point to sustained growth. Mordor Intelligence estimates the European collagen supplements market at USD 0.88 billion in 2025, rising to USD 1.41 billion by 2031 at an 8.22% CAGR. Its analysis also identifies drinks and shots as a faster-growing format, forecasting a 9.93% CAGR for that segment through 2031.
Mordor Intelligence — Europe Collagen Supplements Market
For supplement companies, these numbers point to a category with room for new product formats, new positioning and brand differentiation — particularly in liquid collagen supplements and ready-to-drink products.
Why Liquid Collagen Is Interesting for Supplement Brands
Powders remain an important collagen format, but liquid products give brands a different proposition: no preparation, a clearly defined serving, convenient consumption and packaging that can become part of the product experience.
This is particularly relevant to beauty-from-within brands, premium supplement companies and businesses looking to create a more convenient daily wellness routine.
- Ready-to-drink daily supplementation
- Convenient on-the-go format
- Premium beauty and wellness positioning
- Different serving sizes and packaging concepts
- Opportunities for multi-SKU product families
- Combination formulations with collagen peptides, vitamins and complementary ingredients
25 ml Collagen Shots: A Ready-to-Drink Format
Sequoya’s 25 ml collagen shot format is designed for brands looking for a compact, ready-to-drink collagen supplement. The format can turn collagen into a simple daily product ritual and can be particularly attractive for travel, e-commerce, premium wellness and beauty-from-within concepts.
For product developers, a shot format also creates opportunities to build multi-pack products, subscription concepts and highly recognisable packaging around a defined daily serving.
Liquid Collagen Concentrates: A Flexible Larger-Format Solution
Liquid collagen concentrates provide a different product architecture. Rather than a single-serving bottle, a larger-format product gives brands more flexibility around serving concepts, packaging and product positioning.
A concentrate can become the foundation for a premium collagen range, particularly when combined with complementary ingredients and a clear brand proposition. It also gives companies the possibility of creating several SKUs around one collagen platform.
What Does the Science Say About Oral Collagen?
Collagen peptides and hydrolyzed collagen have been studied extensively as oral supplements. The strongest areas of research include skin-related outcomes and musculoskeletal health, although the quality and consistency of evidence vary between studies.
Skin Health: What the Research Shows
A systematic review and meta-analysis published in 2023 analysed 26 randomized controlled trials involving 1,721 participants. The authors reported statistically significant improvements in skin hydration and elasticity with hydrolyzed collagen compared with placebo, while also noting biases in the included trials and the need for larger, high-quality studies.
PubMed — Effects of Oral Collagen for Skin Anti-Aging: Systematic Review & Meta-Analysis
A newer 2025 systematic review and meta-analysis analysed 23 randomized controlled trials involving 1,474 participants. The pooled analysis of all trials reported improvements in skin hydration, elasticity and wrinkles. However, the authors found that studies without pharmaceutical-company funding and higher-quality studies did not show significant effects, highlighting the importance of study quality and funding when interpreting collagen research.
PubMed — Effects of Collagen Supplements on Skin Aging: Systematic Review & Meta-Analysis, 2025
A 2026 systematic review of 25 randomized controlled trials likewise found improvements in several skin parameters in many trials, while concluding that the evidence remains inconsistent and that more standardized, adequately powered and longer-term trials are needed.
PubMed — Efficacy and Safety of Hydrolyzed Collagen Supplementation on Skin Health Outcomes, 2026
Musculoskeletal Health: Another Major Research Area
Collagen research also extends into musculoskeletal health. A 2024 trial-sequential meta-analysis evaluated 35 randomized controlled trials involving 3,165 participants and assessed collagen derivatives in osteoarthritis. The study reported clinically relevant evidence for some outcomes while also assessing risk of bias and certainty of evidence.
Osteoarthritis and Cartilage — Efficacy and Safety of Collagen Derivatives for Osteoarthritis
A broader 2026 umbrella review examined 16 systematic reviews covering 113 randomized controlled trials and 7,983 participants. The review reported generally favourable associations for skin and musculoskeletal outcomes, while the underlying evidence still varies by outcome, formulation and study quality.
PubMed Central — Collagen Supplementation for Skin and Musculoskeletal Health: Umbrella Review
What the Science Means for Product Developers
The research makes collagen an interesting ingredient for beauty, wellness and functional nutrition products, but it does not mean that every collagen product can make the same claims. Results can vary according to collagen source, peptide profile, dose, duration, study population and finished formulation.
For brands developing collagen supplements in Europe, scientific evidence should therefore be considered alongside regulatory requirements and the exact formulation being marketed.
Collagen Formulation: Beyond a Single Ingredient
Collagen can serve as the foundation for a broader product concept. Depending on the target positioning, brands may explore formulations combining collagen peptides with vitamins and other complementary ingredients.
- Collagen peptides
- Vitamin C
- Selected B vitamins
- Biotin
- Vitamin D
- Zinc
- Hyaluronic acid
- Other complementary beauty and wellness ingredients
The appropriate combination depends on the target market, serving size, regulatory requirements, sensory profile, stability and intended product positioning. The objective should be to create a differentiated finished product rather than simply another generic collagen SKU.
From Product Concept to Private Label Collagen Supplement
For supplement brands, collagen manufacturing involves much more than sourcing collagen peptides. The commercial product needs a coherent formulation, practical dosage, suitable liquid system, sensory profile, packaging and manufacturing process.
- Product concept: Define the target consumer, format, positioning and desired product experience.
- Ingredient selection: Select collagen peptides and complementary ingredients appropriate to the concept.
- Formulation: Develop a stable, practical liquid formulation and serving concept.
- Samples: Evaluate the product and refine formulation and sensory characteristics.
- Manufacturing: Move from approved sample to consistent commercial production.
- Private label packaging: Deliver the finished product in packaging aligned with the client’s brand.
Why Work With a European Collagen Contract Manufacturer?
For brands entering a new supplement category, working with an experienced contract manufacturer can reduce development complexity and allow the brand to focus on positioning, distribution and customer acquisition.
Sequoya Biotechnologies works with brands and NPD teams on supplement development and manufacturing. Our existing contract manufacturing approach covers product development, sampling, production and private-label execution.
The new collagen portfolio extends this approach into liquid collagen supplements, with 25 ml collagen shots and larger-format liquid collagen concentrates designed for brands looking for differentiated products.
Collagen, Beauty From Within and the Next Generation of Supplements
The appeal of collagen is not based on one trend alone. It sits at the intersection of beauty-from-within, wellness, healthy ageing, functional nutrition and convenient daily supplementation.
For brands, this creates an opportunity to build product families rather than isolated SKUs: a 25 ml collagen shot for convenience, a larger liquid collagen concentrate for a different serving concept, and complementary formulations designed around the brand’s target consumer.
The strongest opportunities are likely to come from brands that combine a credible formulation with a clear product story, distinctive packaging and a format that fits the consumer’s routine.
EU Regulatory Considerations for Collagen Claims
Scientific research and permitted marketing claims are not the same thing. In the European Union, health claims for foods and food supplements are governed by Regulation (EC) No 1924/2006 and the EU Register of Nutrition and Health Claims.
EU Register — Collagen Hydrolysate Claim Entry (PDF)
The EU Register includes non-authorised claims relating to collagen hydrolysate, including proposed claims concerning joint cartilage and connective tissues. Brands should therefore review the intended formulation, dosage and marketing claims before finalising labels, product pages or advertising.
Why Liquid Collagen Is a Strong Product Development Opportunity
- A large and growing category — Multiple market analyses project sustained growth in collagen and collagen supplements.
- Strong European relevance — Europe represents a major collagen market with significant consumer interest in beauty and wellness.
- Growing interest in liquid formats — Ready-to-drink shots and liquid products provide convenience and product differentiation.
- Multiple consumer need states — Collagen can be positioned across beauty-from-within, wellness, healthy ageing and musculoskeletal-focused portfolios.
- Multiple SKU opportunities — Brands can build product families around different formats, formulations and serving concepts.
Build Your Next Collagen Product With Sequoya
Collagen is becoming an increasingly important category for supplement brands, but the opportunity is not simply to launch another collagen product. The opportunity is to create a product with the right format, formulation, positioning and consumer experience.
Sequoya Biotechnologies’ new collagen product line provides brands with two liquid formats — 25 ml collagen shots and liquid collagen concentrates — together with contract manufacturing and private-label development capabilities.
If your brand is considering a new collagen supplement, contact the Sequoya NPD team to discuss your product concept, formulation and manufacturing requirements.
To learn more about Sequoya Biotechnologies’ white label adaptogen oil portfolio or to discuss custom formulation development, contact the team at +48-731-563-111 (Europe) or sales@sequoyabio.com, or visit the product pages.
